任娜;赵宏娟;杨雪;刘曼嘉;赵晓春;

• 1:沈阳二四二医院麻醉科
• 2:中国医科大学附属盛京医院麻醉科

摘要(Abstract)：

目的评价酮咯酸氨丁三醇在小儿日间手术中的应用。方法选取2018年2月至2020年2月于沈阳二四二医院行扁桃体切除术患儿60例,年龄2～7岁,采用随机数字表法均分为酮咯酸氨丁三醇组(A组)和生理盐水对照组(B组),每组30例。患儿入室前20 min, A组给予酮咯酸氨丁三醇0.5 mg/kg, B组给予等量生理盐水对照。记录手术结束后1 h(T_1)、2 h(T_2)、4 h(T_3)的FLACC评分,拔管后10 min(T_4)、30 min(T_5)的PAED躁动评分和Ramsay镇静评分,并记录患儿出现皮肤红疹、恶心、呕吐不良反应的发生情况。结果 A组的FLACC评分和PAED躁动评分低于B组,差异有统计学意义(P<0.05)。两组Ramsay镇静评分和不良反应发生情况比较,差异无统计学意义(P>0.05)。结论酮咯酸氨丁三醇在小儿日间手术中能够减轻患儿术后疼痛,减少躁动的发生,无镇静作用,不增加术后不良反应发生率,可安全应用于小儿外科日间手术中。

关键词(KeyWords)： 酮咯酸氨丁三醇;镇痛;日间手术;儿童

Abstract:

Keywords:

基金项目(Foundation): 沈阳市中青年科技创新人才支持计划(RC190498)

作者(Authors): 任娜;赵宏娟;杨雪;刘曼嘉;赵晓春;

DOI: 10.14053/j.cnki.ppcr.202108010

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