儿科多重耐药肺炎克雷伯菌的检测及其耐药性分析Analysis of detection and drug resistance of multidrug-resistant Klebsiella pneumoniae in pediatric patients
岳冬梅;王忻;李崇;刘畅;
摘要(Abstract):
目的观察我院儿科住院患者多重耐药肺炎克雷伯菌的临床分布特点及其耐药性,为儿科脓毒症感染的治疗提供诊治依据。方法收集2016年1月至2018年1月我院儿科住院患者的各类送检标本,行细菌鉴定和药敏分析。结果共检出肺炎克雷伯菌744株,其中检出最多的是血液标本,其次是痰液和尿液标本,分别占48.52%、31.59%、10.49%;患儿科室分布以NICU和PICU为主,分别占63.04%、20.83%。多重耐药肺炎克雷伯菌对氨苄西林、头孢呋辛、头孢唑啉、头孢噻肟、头孢曲松、头孢吡肟的耐药严重,而对哌拉西林/他唑巴坦、碳青霉烯类药物、阿米卡星均敏感。结论儿科住院患者对肺炎克雷伯菌的耐药率均较高,尤其是ICU患儿,医生应该加强对抗生素的管理,合理、规范地使用,预防肺炎克雷伯菌的医院感染的暴发。
关键词(KeyWords): 多重耐药肺炎克雷伯菌;脓毒症;病原菌;儿童
基金项目(Foundation):
作者(Authors): 岳冬梅;王忻;李崇;刘畅;
DOI: 10.14053/j.cnki.ppcr.201806025
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